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Phenyl ester side chain to increase polymer absorbency
专利权人:
タイレックス・インコーポレイテッド
发明人:
シュウォーツ,アーサー,プラプラ,サティッシュ,ネサラ,サリタ,シュウォーツ,アーサー,プラプラ,サティッシュ,ネサラ,サリタ
申请号:
JP2010513454
公开号:
JP6046331B2
申请日:
2008.06.20
申请国别(地区):
JP
年份:
2016
代理人:
摘要:
The present invention relates to polymers modified to increase their resorbability. In particular, the polymers of the invention have phenyl ester side chains which are good leaving groups and which thereby increase the resorption rate of the polymer relative to the same polymer, for example, bearing a comparable amount of an alkyl ester side chain. Such polymers are generally water insoluble, but when modified are able to solublize drugs and upon degradation and resorption, release those in a physiological environment in a controlled and/or sustained manner.
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中国工程科技知识中心
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