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CHAÎNES LATÉRALES D'ESTER DE PHÉNYLE PERMETTANT D'ACCROÎTRE LA CAPACITÉ DE RÉSORPTION DES POLYMÈRES
专利权人:
INC.;TYRX
发明人:
SCHWARTZ, ARTHUR,PULAPURA, SATISH,NETHULA, SARITA
申请号:
EP08780892
公开号:
EP2166981A4
申请日:
2008.06.20
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
The present invention relates to polymers modified to increase their resorbability. In particular, the polymers of the invention have phenyl ester side chains which are good leaving groups and which thereby increase the resorption rate of the polymer relative to the same polymer, for example, bearing a comparable amount of an alkyl ester side chain. Such polymers are generally water insoluble, but when modified are able to solublize drugs and upon degradation and resorption, release those in a physiological environment in a controlled and/or sustained manner.
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中国工程科技知识中心
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