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N-(4-((3-(2-AMINO-4-PIRlMIDlNIL)-2-PIRlDlNlL)OKSI)FENIL)-4-(4-METIL-2-THIENIL)- 1-FTALAZINAMIN ZA PRIMENU U TRETMANU KANCERA REZISTENTNOG NA ANTIMITOTIČKE AGENSE
专利权人:
Amgen; Inc
发明人:
PAYTON, Marc,KENDALL, Richard
申请号:
MEP1015
公开号:
ME02048B
申请日:
2010.09.09
申请国别(地区):
ME
年份:
2015
代理人:
摘要:
The present invention relates to methods of using the compound, N-(4-((3-(2-amino-4-pyrimidinyl)-2-pyridinyl)oxy)phenyl)-4-(4-methyl-2-thienyl)-1-phthalazinamine or a pharmaceutically acceptable salt thereof, to treat cancers, including solid tumors, which have become resistant to treatment with chemotherapeutic agents, including anti-mitotic agents such as taxanes, and/or other anti-cancer agents, including aurora kinase inhibiting agents. The invention also includes methods of treating cancers refractory to such treatments by administering a pharmaceutical composition, comprising the compound to a cancer subject.text
来源网站:
中国工程科技知识中心
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