Bacterially-derived, intact minicells that encompass plasmid-free functional nucleic acid for in vivo delivery to mammalian cells

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专利权人:

EnGeneIC Molecular Delivery Pty Ltd.

发明人:

Himanshu Brahmbhatt,Jennifer MacDiarmid,Toby Hulf

申请号：

US14207304

公开号：

US09066982B2

申请日:

2014.03.12

申请国别(地区):

US

年份:

2015

代理人:

摘要：

Intact, bacterially-derived minicells can safely introduce therapeutically effective amount of plasmid-free functional nucleic acid to target mammalian cells. To this end, functional nucleic acid can be packaged into intact minicells directly, without resort to expression constructs, the expression machinery of the host cell, harsh chemicals or electroporation.

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中国工程科技知识中心

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