Bacterially-derived, intact minicells that encompass plasmid-free functional nucleic acid for in vivo delivery to mammalian cells

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专利权人:

EnGeneIC Molecular Delivery Pty. Ltd.

发明人:

Macdiarmid, Jennifer,Brahmbhatt, Himanshu,Hulf, Toby

申请号：

AU2008291833

公开号：

AU2008291833B2

申请日:

2008.03.26

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

Intact, bacterially-derived minicells can safely introduce therapeuticallyeffective amounts of plasmid-free functional nucleic acid to target mammaliancells. To this end, functional nucleic acid can be packaged into intact minicellsdirectly, without resort to expression constructs, the expression machineryof the host cell, harsh chemicals or electroporation.

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中国工程科技知识中心

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