The present invention discloses a manufacturing and separating device for oily radioactive substance and the method thereof, which provides a hepatic artery injection automatic synthesis box By means of the method and device according to the present invention, the oily radioactive substance can be automatically manufactured, which can not only significantly reduce the personnel cost and man-made errors in mass production, but also can decrease the radioactive exposure of the manufacturing staff during the manufacturing process so as to provide better radioactive protection for the manufacturing staff.本發明係一種油狀放射物質的研製與分離裝置與方法,提供一種肝動脈注射劑自動合成盒,經由本發明將可以自動化生產油狀放射物質,在大量生產中降低人事成本與人為操作因素,並且可以減少製備過程中人員輻射暴露,使製備人員獲得更好的輻射防護。11‧‧‧第一反應原料瓶12‧‧‧第一加熱器121‧‧‧第二反應原料瓶122‧‧‧第一放射活度偵測器13‧‧‧氣體幫浦14‧‧‧第一沖洗材料瓶15‧‧‧第二沖洗材料瓶16‧‧‧純化裝置17‧‧‧第一輸送單元18‧‧‧可控溫暫存槽19‧‧‧過濾器20‧‧‧第一收集瓶201‧‧‧第二放射活度偵測器21‧‧‧第二收集瓶22‧‧‧第二輸送單元23‧‧‧廢液回收瓶24‧‧‧第三輸送單元25‧‧‧第三沖洗材料瓶3‧‧‧閥門4‧‧‧控制單元