Henrik NILSSON,Florian SCHOENHARTING,Bernd W. MUELLER,Joseph R. ROBINSON
申请号：
US14213321
公开号：
US20140199387A1
申请日:
2014.03.14
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to controlled release pharmaceutical compositions comprising fumaric acid ester(s) as active substance(s). The compositions are suitable for use in the treatment of e.g. psoriasis or other hyperproliferative, inflammatory or autoimmune disorders and are designated to release the fumaric acid ester in a controlled manner so that local high concentrations of the active substance within the gastrointestinal tract upon oral administration can be avoided and, thereby, enabling a reduction in gastro-intestinal related side-effects.
