SCHOENHARTING, FLORIAN,MUELLER, BERND W,ROBINSON, JOSEPH R.,NILSSON, HENRIK
申请号:
DK10182198
公开号:
DK2316430T3
申请日:
2005.10.07
申请国别(地区):
DK
年份:
2012
代理人:
摘要:
The present invention relates to controlled release pharmaceutical compositions comprising fumaric acid ester(s) as active substance(s). The compositions are suitable for use in the treatment of e.g. psoriasis or other hyperproliferative, inflammatory or autoimmune disorders and are designed to release the fumaric acid ester in a controlled manner so that local high concentrations of the active substance within the gastrointestinal tract upon oral administration can be avoided and, thereby, enabling a reduction in gastro-intestinal related side-effects.