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CROSS-LINKED HA BEADS AND PROCESS FOR MAKING SAME
专利权人:
Prollenium Medical Technologies; Inc.
发明人:
Hitoshi Masui
申请号:
US16661683
公开号:
US20200123276A1
申请日:
2019.10.23
申请国别(地区):
US
年份:
2020
代理人:
摘要:
This disclosure provides a hyaluronic acid (HA) bead, a dermal filler having hyaluronic acid (HA) and a process for preparing the HA beads. The process includes combining an HA compound with sodium hydroxide, forming an HA solution, and injecting the HA solution into an oil solution, and forming an emulsion with HA beads. A cross-linking reagent is added and the mixture is stirred for 24 hours in room temperature, thereby forming cross-linked HA beads. The HA beads are cross-linked and adapted to dissolve in vivo upon contact with hyaluronidase.
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