PROCÉDÉS, COMPOSÉS ET COMPOSITIONS DESTINÉS À MODULER L'INTÉGRITÉ DE LA BARRIÈRE HÉMATO-ENCÉPHALIQUE ET LA REMYÉLINISATION

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专利权人:

University Health Network

发明人:

申请号：

EP16847698.4

公开号：

EP3352778A4

申请日:

2016.09.23

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

Disclosed herein are methods and compositions for increasing and decreasing the permeability of the blood brain barrier for the treatment of diseases and conditions and to facilitate the delivery of agents to the brain, as well as methods and compositions for promoting re-myelination and preventing de-myelination. Compositions include RGMa, soluble RGMa, and functional fragments and variants thereof, RGMc, soluble RGMc, and functional fragments and variants thereof, and Neogenin peptides including 4Ig.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/