Hausdorff, William P.,Siber, George Rainer,Paradiso, Peter R.
申请号：
AU2011253684
公开号：
AU2011253684B8
申请日:
2011.11.25
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
#$%^&*AU2011253684B820130711.pdf#####C: NRPv tblDCC AMTh0143 lOI.DOC-2411 l2011 MULTIVALENT PNEUMOCOCCAL POLYSACCHARIDE-PROTEIN CONJUGATE COMPOSITION ABSTRACT An immunogenic composition having 13 distinct polysaccharide-protein conjugates and optionally, an aluminum-based adjuvant, is described. Each conjugate contains a capsular polysaccharide prepared from a different serotype of Streptococcus pneumoniae (1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F) conjugated to a carrier protein. The immunogenic composition, formulated as a vaccine, increases coverage against pneumococcal disease in infants and young children globally, and provides coverage for serotypes 6A and 19A that is not dependen t on the limitations o f s erogroup c rossprotection.
