HAUSDORFF, William P.,SIBER, George Rainer,PARADISO, Peter R.
申请号:
AU2018213968
公开号:
AU2018213968A1
申请日:
2018.08.06
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
#$%^&*AU2018213968A120180823.pdf#####C:\NRPortb\DCC\AM4014380_I.DOC-24/11/2011 MULTIVALENT PNEUMOCOCCAL POLYSACCHARIDE-PROTEIN CONJUGATE COMPOSITION ABSTRACT An immunogenic composition having 13 distinct polysaccharide-protein conjugates and optionally, an aluminum-based adjuvant, is described. Each conjugate contains a capsular polysaccharide prepared from a different serotype of Streptococcus pneumoniae (1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F) conjugated to a carrier protein. The immunogenic composition, formulated as a vaccine, increases coverage against pneumococcal disease in infants and young children globally, and provides coverage for serotypes 6A and 19A that is not dependen t on the limitations o f s erogroup c rossprotection.