HUTCHINSON, JOHN HOWARD,BLEICHER, LEO,COSFORD, NICK,ARDECKY, ROBERT JOHN,ZOU, JIWEN
申请号：
CA2847247
公开号：
CA2847247A1
申请日:
2012.08.29
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present invention relates to novel benzodiazepinone compounds of Formulae (I) wherein R1, R2, R4, R6, R7, R8, R9, and R10 are as defined herein. The invention also relates to pharmaceutical compositions containing such compounds, methods of use of such compounds and compositions, and methods for preparing the compounds and compositions. The compounds are Group II metabotropic glutamate antagonists or allosteric modulators and are useful for the treatment of a variety of CNS disorders.
