Leo Bleicher;Nick Cosford;Robert John Ardecky;John Howard Hutchinson;Jiwen Zou
发明人:
John Howard Hutchinson,Leo Bleicher,Nick Cosford,Robert John Ardecky,Jiwen Zou
申请号：
US14342339
公开号：
US20150025064A1
申请日:
2012.08.29
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention relates to novel benzodiazepinone compounds of Formulae (I)wherein R1, R2, R4, R6, R7, R8, R9, and R10 are as defined herein. The invention also relates to pharmaceutical compositions containing such compounds, methods of use of such compounds and compositions, and methods for preparing the compounds and compositions. The compounds are Group II metabotropic glutamate antagonists or allosteric modulators and are useful for the treatment of a variety of CNS disorders.
