Ching-Shih Chen,Matthew David Ringel,Motoyashi Saji,Yihui Ma
申请号：
US14230689
公开号：
US09156790B2
申请日:
2014.03.31
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Compounds according to formula I:wherein Ar is a fused aryl group, R1 is selected from alkyl and aryl amides, CF3, and CH2OH, and R2 is selected from hydrogen, —C(═O)CH2NH2, and —C(═O)CH2CH2NH2 are described. The compounds are effective for inhibiting p21-activated kinases, and can be used for prevention and treatment of cancer.
