The present disclosure provides a formulation comprising an agriculturally acceptable carrier and liposomes comprising a lipid membrane and an intraliposomal aqueous core, wherein, the liposome has a diameter in the range of between 100nm to 300nm; and the lipid membrane comprise at least one liposome forming phospholipid. Specifically, the lipid membrane comprise two or more phospholipids, at least one of said two or more phospholipids is a liposome forming lipid, and at least one of said two or more phospholipids is characterized by one or more of the following features: (a) it has an unsaturated lipid tail; (b) it comprise a polar head group; (c) it comprises an acidic head group. Also disclosed herein are methods of using the formulation for agricultural treatment and kits for preparing and using such formulations.