PROCESS LINE FOR THE PRODUCTION OF FREEZE-DRIED PARTICLES

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专利权人:

SANOFI PASTEUR SA

发明人:

LUY, BERNHARD,PLITZKO, MATTHIAS,STRUSCHKA, MANFRED

申请号：

MYPI 2014000743

公开号：

MY151369A

申请日:

2012.10.04

申请国别(地区):

MY

年份:

2014

代理人:

摘要：

A PROCESS LINE (102) FOR THE PRODUCTION OF FREEZE-DRIED PARTICLES UNDER CLOSED CONDITIONS (104) IS PROVIDED, THE PROCESS LINE COMPRISING AT LEAST THE FOLLOWING SEPARATE DEVICES: A SPRAY CHAMBER FOR DROPLET GENERATION AND FREEZE CONGEALING OF THE LIQUID DROPLETS TO FORM PARTICLES, AND A BULK FREEZE-DRYER (304) FOR FREEZE DRYING THE PARTICLES, WHEREIN A TRANSFER SECTION IS PROVIDED FOR A PRODUCT TRANSFER FROM THE SPRAY CHAMBER TO THE FREEZE-DRYER, FOR THE PRODUCTION OF THE PARTICLES UNDER END-TO-END CLOSED CONDITIONS EACH OF THE DEVICES AND OF THE TRANSFER SECTION IS SEPARATELY ADAPTED FOR CLOSED OPERATION, AND THE SPRAY CHAMBER IS ADAPTED FOR SEPARATION OF THE LIQUID DROPLETS (323) FROM ANY COOLING CIRCUIT. (FIGURE 3)

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