William R. Jacobs, Jr.,Steven A. Porcelli,Volker Briken,Miriam Braunstein
申请号：
US11794506
公开号：
US08394388B2
申请日:
2006.01.12
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Provided are recombinant mycobacteria having a mutation in an nlaA gene or in a nuoG gene. Also provided are isolated and purified nlaA proteins and nuoG proteins from a mycobacterium. Additionally provided are isolated and purified nucleic acids comprising a recombinant nlaA gene or a recombinant nuoG gene. Further provided are methods of inducing an immune response in a mammal and methods of making a recombinant mycobacterium using the nlaA gene or the nuoG gene.
