Aminotetralin derivatives, pharmaceutical compositions containing them and their use in therapy

• 收藏
• 分享

专利权人:

AbbVie Deutschland GmbH & Co KG;AbbVie Inc.

发明人:

AMBERG, Wilhelm,OCHSE, Michael,LANGE, Udo,KLING, Andreas,BEHL, Berthold,HORNBERGER, Wilfried,MEZLER, Mario,HUTCHINS, Charles

申请号：

ES10706575

公开号：

ES2584002T3

申请日:

2010.02.16

申请国别(地区):

ES

年份:

2016

代理人:

摘要：

A compound of formula (I) ** Formula ** where A is a ring selected from the group consisting of the following 5 or 6 membered heterocyclic rings: ** Formula ** A is a benzene ring and the compound has the following formula : ** Formula ** R is R1-W-A1-QY-A2-X1-； R1 is hydrogen, C1-C6 alkyl, C3-C12 cycloalkyl-C1-C4 alkyl, halogenated C1-C6 alkyl, tri- (C1-C4 alkyl) -syl-C1-C4 alkyl, C1-C4 hydroxyalkyl, C1-C6 alkoxy C1-C4, C1-C4 aminoalkyl, C1-C6 alkylamino-C1-C4 alkyl, C1-C6 dialkylamino-C1-C4 alkyl, C1-C6 alkylcarbonylamino-C1-C4 alkyl, C1-C6 alkyloxycarbonylamino-C1-C4 alkyl alkylaminocarbonylamino C1-C6-C1-C4 alkyl, di-alkylaminocarbonylamino C1-C6-C1-C4 alkyl, C1-C6 alkylsulfonylamino-C1-C4 alkyl, (optionally substituted C6-C12-C1-C6 alkyl) C1-C4 aminoalkyl, aryl C6-C12-optionally substituted C1-C4 alkyl, optionally substituted C3-C12-heterocyclyl-C1-C4 alkyl, C3-C12 cycloalkyl, C1-C6 alkylcarbonyl, C1-C6 alkoxycarbonyl, halogenated C1-C6 alkoxycarbonyl, C6-C12 aryloxycarbonyl, aminocarbonyl , C1-C6 alkylaminocarbonyl, (halogenated C1-C4 alkyl) aminocarbonyl, C6-C12 arylaminocarbonyl, C2-C6 alkenyl, C2-C6 alkynyl, optionally substituted C6-C12 aryl, hydroxy, a C1-C6 alkoxy, halogenated C1-C6 alkoxy, C1-C6 hydroxyalkoxy, C1-C6 alkoxy-C1-C4 alkoxy, C1-C4 alkoxy, C1-C6 alkylamino-C1-C4 alkoxy, C1-C6 alkylamino-C1-C4 alkoxy , C1-C6 alkylcarbonylamino-C1-C4 alkoxy, C6-C12-arylcarbonylamino-C1-C4 alkoxycarbonylamino C1-C6-C1-C4 alkoxy, aryl C6-C12-C1-C4 alkoxy, alkylsulfonylamino C1-C6-C1-C4 alkoxy , (halogenated C1-C6 alkyl) C1-C4 sulfonylaminoalkoxy, C6-C12-arylsulfonylamino C1-C4, (C6-C12-aryl-C1-C6 alkyl) sulfonylaminoalkoxy C1-C4, heterocyclylsulfonylamino C3-C12-C1-C4 alkoxy heterocyclyl C3-C12-C1-C4 alkoxy, C6-C12 aryloxy, C3-C12 heterocyclyloxy, C1-C6 alkylthio, halogenated C1-C6 alkylthio, C1-C6 alkylamino, (halogenated C1-C6 alkyl) amino, C1-C6 alkylamino , di- (halogenated C1-C6 alkyl) amino, C1-C6 alkylcarbonylamino, (halogenated C1-C6 alkyl) carbonylamino,

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/