Aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy

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专利权人:

ABBVIE DEUTSCHLAND GMBH & CO. KG;ABBVIE INC.

发明人:

LANGE, UDO,AMBERG, WILHELM,OCHSE, MICHAEL,POHLKI, FRAUKE,BEHL, BERTHOLD,HUTCHINS, CHARLES

申请号：

ES11757790

公开号：

ES2526074T3

申请日:

2011.08.12

申请国别(地区):

ES

年份:

2015

代理人:

摘要：

Aminoindane derivatives of the formula (I) ** Formula ** where A is a 5 or 6 member ring； R is R1-W-A1-Q-Y-A2-X1-； R1 is hydrogen, C1-C6 alkyl, C3-C12 cycloalkyl-C1-C4 alkyl, halogenated C1-C6 alkyl, tri- (C1-C4 alkyl) -silyl C1-C4 alkyl, hydroxy-C1-C4 alkyl, C1 alkoxy -C6-C1-C4 alkyl, amino-C1-C4 alkyl, C1-C6 alkylamino-C1-C4 alkyl, di-C1-C6 alkylamino-C1-C4 alkyl, C1-C6 alkylcarbonylamino-C1-C4 alkyl, C1- alkyloxycarbonylamino C6-C1-C4 alkyl, C1-C6 alkylaminocarbonylamino-C1-C4 alkyl, C1-C6 alkylaminocarbonylamino-C1-C4 alkyl, C1-C6 alkylsulfonylamino-C1-C4 alkyl, (C6-C12 aryl-C1-C6 alkyl optionally substituted) amino-C1-C4 alkyl, aryl C6-C12-optionally substituted C1-C4 alkyl, optionally substituted C3-C12 heterocyclyl-C1-C4 alkyl, C3-C12 cycloalkyl, C1-C6 alkylcarbonyl, C1-C6 alkoxycarbonyl, C1 alkoxycarbonyl -C6 halogenated, C6-C12 aryloxycarbonyl, aminocarbonyl, C1-C6 alkylaminocarbonyl, (halogenated C1-C4 alkyl) aminocarbonyl, C6-C12 arylaminocarbonyl, C2-C6 alkenyl, optionally substituted C2-C6 alkynyl, hydroxy, C1-C6 alkoxy, halogenated C1-C6 alkoxy, C1-C6 hydroxyalkoxy, C1-C6 alkoxy-C1-C4 alkoxy, C1-C4 alkoxy, C1-C4 alkylamino-C1-C6 alkoxy, C1-C6 alkylamino C1-C4 alkoxy, C1-C6 alkylcarbonylamino-C1-C4 alkoxy, C6-C12 arylcarbonylamino-C1-C4 alkoxy, C1-C6 alkoxycarbonylamino-C1-C4 alkoxy, C6-C12-aryl-C1-C4 alkoxy, C1-C6 alkylsulfonylamino C1-C4 alkoxy, (halogenated C1-C6 alkyl) sulfonylamino-C1-C4 alkoxy, C6-C12-arylsulfonylamino-C1-C4 alkoxy, (C6-C12-aryl-C1-C6 alkyl) sulfonylamino-C1-C4 alkoxy, heterocyclylsulfonylamino C3- C12-C1-C4 alkoxy, C3-C12 heterocyclyl-C1-C4 alkoxy, C6-C12 aryloxy, C3-C12 heterocyclyloxy, C1-C6 alkylthio, halogenated C1-C6 alkylthio, C1-C6 alkylamino, (halogenated C1-C6 alkyl) amino, C1-C6 di-alkylamino, halogenated C1-C6 alkyl) amino, C1-C6 alkylcarbonylamino, (halogenated C1-C6 alkyl) carbonylamino, C6-C12 arylcarbonylamino, C1-C6 alkylsulfonylamino, (halogenated C1-C6 alkyl ) sulfonylamino, C6-C12 arylsulfonylamino or C3-C12 he

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