PURPOSE: The egg york immunoglobulin is provided to manufacture the honeybee fooder which has the antibacterial activity about a causal body of foulbrood, no toxicity in vivo, high safety. CONSTITUTION: The egg york immunoglobulin added composition is manufactured as following step. A Panibacillus larval strain is transplanted to the culture medium and cultured in 25 °；C for more than 48 hours, before a typical singleness colony is selected and subcultured in the culture medium respectively. The spawn is inoculated to 20 % of subcultured culture medium cultivate in 25 °；C with 5-7 days. After the cultivated culture medium is inactivated by adding 0.3% formalin, collect the fungus body with centrifugation. An immuno-regulator is manufactured by usinge fungi a spectrophotometer and a homogenizer, after two times of centrifugal washing. The Immuno-regulator is inoculated to a layer chicken, and the egg in which immunity is formed is hygienically collected, and completely dry. The egg york immunoglobulin powder in which the moisture content of the immunity formed egg yolk is less than 10% is manufactured by spraying process of the nozzle form and disc. A pollen 2.0 kg, yeast 0.5 kg, soybean flour 2.0 kg, the egg york immunoglobulin (IgY) 1-5 kg, distilled water 1.9 kg are mixed. The egg york immunoglobulin is produced by injecting a antigen component of the Paenibacillus larvae.본 발명은 페니바실러스 라베(Paenibacillus larvae)의 항원성분을 닭에 주입하여 생산된 난황면역항체(IgY)성분을 포함하여 조성되어 있음을 특징으로 하는 난황면역항체 첨가 조성물이 함유된 꿀벌사료 및 그 제조방법.
