An instrument system for phacoemulsification includes a femto- or picosecond laser device configured to dissect a lens of a patient's eye into lens fragments, open an anterior capsule of the lens of the eye, and make an incision in the eyeball so as to provide access to the lens of the eye. The system also includes device for fragmenting and aspirating the lens fragments through the access incision. A monitoring device is provided for monitoring results achieved by the phacoemulsification. A control device is configured to control the femto- or picosecond laser device and the device for fragmenting and aspirating the lens fragments, subject to parameters of the eye to be treated or of given surgical steps.