Stefan Peters;Frank Himmelsbach;Matthias Eckhardt;Bradford S. Hamilton;Joerg Kley
发明人:
Stefan Peters,Matthias Eckhardt,Bradford S. Hamilton,Frank Himmelsbach,Joerg Kley
申请号：
US14191951
公开号：
US09073870B2
申请日:
2014.02.27
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention relates to compounds defined by formula Iwherein the groups A, B, X, m, n and o are defined as in claim 1, possessing valuable pharmacological activity. Particularly the compounds are inhibitors of 11β-hydroxysteroid dehydrogenase (HSD) 1 and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this enzyme, such as metabolic diseases, in particular diabetes type 2, obesity and dyslipidemia.
