Thorsten Lehmann-Lintz;Bradford S. Hamilton;Joerg Kley
发明人:
Bradford S. Hamilton,Joerg Kley,Thorsten Lehmann-Lintz
申请号：
US12991722
公开号：
US08765780B2
申请日:
2009.05.12
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to compounds defined by Formula (I),wherein the groups A, B, X, m, n and o are defined as in claim 1, possessing valuable pharmacological activity. Particularly the compounds are inhibitors of 11β-hydroxysteroid dehydrogenase (HSD) 1 and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this enzyme, such as metabolic diseases, in particular diabetes type 2, obesity and dyslipidemia.
