University of South Carolina;MUSC Foundation for Research Development
发明人:
Michael John Yost,Veronica Rodriguez-Rivera
申请号：
US15514091
公开号：
US20170247430A1
申请日:
2015.09.28
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Methods for reaction electrospinning are provided to form collagen fibers. The method can include: acidifying a collagen in an acidic solvent to form an acidic collagen solution； electrospinning the acidic collagen solution within an alkaline atmosphere (e.g., including ammonia vapor) to form collagen fibers； and collecting the collagen fibers within a salt bath (e.g., including ammonium sulfate). The acidic solvent can include water and an alcohol, and can have a pH of about 2 to about 4 (e.g., including a strong acid, such as HCl). An albumin rubber is also provided, which can include albumin crosslinked with glutaraldehyde.
