Ramon Alemany Bonastre,Juan Jose Rojas Exposito,Manel Maria Cascallo Piqueras
申请号：
US15144637
公开号：
US10016470B2
申请日:
2016.05.02
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The invention relates to an oncolytic adenovirus for the treatment of cancer, containing a human DNA sequence isolating a promoter conferring selective expression on an adenoviral gene. Said adenovirus can also contain a sequence that optimizes the protein translation of an adenoviral gene regulated by a promoter conferring tumor selectivity. The invention is suitable for use in the treatment of cancer.
