A flexible adhesive kinesiology/physio tape of the present invention adapted adapted to provide thermo-dynamic cooling. In a most general embodiment, the inventive tape includes flexible adhesive kinesiology or physio tape with thermal cooling properties including: a first layer of flexible adhesive high quality porous fabric； a second layer of flexible self-adhesive or skin adhesive high quality porous fabric； and a third layer of flexible endothermic material, sandwiched between the first and second layers. In the illustrative embodiment, the tape is a sheet of high quality porous fabric with a blend of cotton, latex or nylon and the third layer is constructed with reactants effective to cause an endothermic chemical reaction. A breakable barrier separates the reactants so cooling can be initiated at any point by manually breaking the barrier. The third layer can be implemented with liquid, with sealed borders, or with solid reactants that could be saturated or interwoven with reactants.
