TRUCHON, JEAN-FRANCOIS,LACHANCE, NICOLAS,LAU, CHEUK K.,LEBLANC, YVES,MELLON, CHRISTOPHE,ROY, PATRICK,ISABEL, ELISE,OTTE, RYAN D.,YOUNG, JONATHAN R.
申请号：
CA2630562
公开号：
CA2630562C
申请日:
2006.11.17
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present invention provides inhibitors of kinases, specifically I.kappa.Bkinases, JAK1,JAK2, JAK3 and TYK2, comprising formula I(see formula I)The invention also provides for compositions comprising such inhibitorycompoundsand methods of inhibiting said kinases activity by administering the compoundto apatient in need of treatment for myeloproliferative disorders, cancer orNF-.kappa.B-mediated diseases.
