Stable pharmaceutical formulation for oral administration comprising levocetirizine or a pharmaceutically acceptable salt thereof and montelukast or a pharmaceutically acceptable salt thereof

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专利权人:

エルティーディー．;ファーム．;ハンミ;ハンミ ファーム. シーオー., エルティーディー.;シーオー．，

发明人:

クォン・テグワン,キム・ドンホ,キム・ギョンス,キム・ヨンイル,パク・ジェヒョン,ウ・ジョンス

申请号：

JP2014551191

公开号：

JP6163165B2

申请日:

2013.01.04

申请国别(地区):

JP

年份:

2017

代理人:

摘要：

The present invention relates to a pharmaceutical formulation for oral administration for preventing or treating allergic rhinitis or asthma, which comprises: (a) a first particle part comprising levocetirizine or a pharmaceutically acceptable salt thereof and an organic acid； and (b) a second particle part comprising montelukast or a pharmaceutically acceptable salt thereof. The pharmaceutical formulation according to the present invention comprises an organic acid as a stabilizing agent, which can effectively inhibit the production of levocetirizine and montelukast related substances, and thus, show good stability.

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中国工程科技知识中心

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