STABLE PHARMACEUTICAL FORMULATION FOR ORAL ADMINISTRATION COMPRISING LEVOCETIRIZINE OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND MONTELUKAST OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF
KWON Taek Kwan,KWON Taek Kwan,KIM Dong Ho,KIM Dong Ho,KIM Kyeong Soo,KIM Kyeong Soo,KIM Yong Il,KIM Yong Il,PARK Jae Hyun,PARK Jae Hyun,WOO Jong Soo,WOO Jong Soo
申请号：
SI201331005
公开号：
SI2800558T1
申请日:
2013.01.04
申请国别(地区):
SI
年份:
2018
代理人:
摘要：
The present invention relates to a pharmaceutical formulation for oral administration for preventing or treating allergic rhinitis or asthma, which comprises: (a) a first particle part comprising levocetirizine or a pharmaceutically acceptable salt thereof and an organic acid and (b) a second particle part comprising montelukast or a pharmaceutically acceptable salt thereof. The pharmaceutical formulation according to the present invention comprises an organic acid as a stabilizing agent, which can effectively inhibit the production of levocetirizine and montelukast related substances, and thus, show good stability.
