Zeren Gao,Phil Tan,Brian R. Kovacevich,Blair R. Renshaw,Jeffrey B. Adamo,Nga Sze Amanda Mak,Shi Zhuo,Lan Chen
申请号:
US15119694
公开号:
US20170073418A1
申请日:
2015.12.19
申请国别(地区):
US
年份:
2017
代理人:
摘要:
A bispecific tetravalent antibody comprising an IgG having a pair of heavy chains and a pair of light chains, and two scFv components being connected to either C or N terminals of the heavy or light chains. The bispecific tetravalent antibody may have a binding specificity for two different members of EGFR family.