Susan Harran;Gunnar J. Hanson;David Thomas;Nizal Chandrakumar
发明人:
Gunnar J. Hanson,David Thomas,Nizal Chandrakumar,Susan Harran
申请号：
US12897760
公开号：
US20120082640A1
申请日:
2010.10.04
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention provides small molecule mimics of the Smac peptide that are dimer- or dimer-like compounds having two amide-containing domains connected by a linker. These compounds are useful to promote apoptosis. The invention includes pharmaceutical compositions comprising such compounds and methods to use them to treat conditions including cancer and autoimmune disorders.
