PROBLEM TO BE SOLVED: To provide an agent and food/drink having osteoclast differentiation inhibitory action and osteoblast differentiation promoting action and useful against osteoporosis.SOLUTION: The present invention provides an osteoblast differentiation promoter or osteoclast differentiation inhibitor containing a kawalactone derivative compound as an active ingredient, and an agent for preventing or improving osteoporosis or rheumatoid arthritis that contains the same.SELECTED DRAWING: NoneCOPYRIGHT: (C)2018,JPO&INPIT【課題】破骨細胞分化抑制作用、骨芽細胞分化促進作用を有し、骨粗鬆症に有用な薬剤や飲食物の提供。【解決手段】カワラクトン誘導体化合物を有効成分として含有する、骨芽細胞分化促進剤または破骨細胞分化抑制剤、並びにそれらを含む骨粗鬆症または関節リウマチの予防または改善剤。【選択図】なし
