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生分解性樹脂複合材料により構成される組織再生用足場(スカフォールド)
专利权人:
公益財団法人新産業創造研究機構
发明人:
日和 千秋,安達 泰治,馬場 俊輔
申请号:
JP2006511277
公开号:
JP4915004B2
申请日:
2005.03.22
申请国别(地区):
JP
年份:
2012
代理人:
摘要:
It is intended to provide a scaffold for tissue regeneration in which cells and etc. can be easily sowed and which can prevent infiltration by a neighboring tissue such as granulation and has an appropriate rigidity and a sufficient strength and the biodegradation of which can be controlled from site to site. Namely and a scaffold is constructed by weaving a polylactic acid resin (PLA) fiber to give a porous woven construct and forming a composite material by using a PCL resin as a binder. Owing to the film structure of the PCL resin coating the woven fiber structure and the rigidity can be elevated by 500 times or above. This rigidity level can be varied by changing the fiber size, the weaving pitch or the film thickness and which makes it possible to broaden the application range thereof to the human body. The film thickness is increased in a part being in contact with the defect part required for the regeneration so that a porous film of 10 mum in pore size can be formed. Immediately after the surgical operation and the pore size is enlarged due to biodegradation by bodily fluids. Thus, the bodily fluids, nutrients, oxygen and etc. in the body can quickly penetrate into the scaffold and thereby providing environment suitable for the growth of osteoblasts or the like.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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