Thiadiazole compounds and 1,2,4 - Oxadiazoles 3 - substituted as immunomodulators

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专利权人:

AURIGENE DISCOVERY TECHNOLOGIES LIMITED

发明人:

Naremaddepalli, Seetharamaiah Setty Sudarshan,Prasad, Appukkuttan,Ramachandra, Muralidhara,Sasikumar, Pottayil Govindan Nair

申请号：

CU20170118

公开号：

CU20170118A7

申请日:

2016.03.09

申请国别(地区):

CU

年份:

2018

代理人:

摘要：

<； p >； The present Invention relates to compounds thiadiazole and 1.2.4 - 3 - substituted Oxadiazoles of formula (i) or formula (ii) and their use for inhibiting the Signaling Pathway of Programmed Cell Death 1 (pd-1) and / or for the treatment of disorders by inhibiting SignalImmunosuppression induced by pd-1 and pd-l1 or PD L2. <； / p >；<；p>；La presente invención se refiere a compuestos de tiadiazol y 1,2,4-oxadiazol 3-sustituidos de fórmula (I) o fórmula (II) y su uso para inhibir la vía de señalización de la muerte celular programada 1 (PD-1) y/o para el tratamiento de trastornos al inhibir una señal inmunosupresora inducida por PD-1, PD-L1 o PD-L2.<；/p>；

来源网站：

中国工程科技知识中心

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