3-substituted-1,2,4-oxadiazole and thiadiazole compounds as immunomodulators

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专利权人:

Aurigene Discovery Technologies Limited

发明人:

Sasikumar, Pottayil Govindan Nair,Ramachandra, Muralidhara,Prasad, Appukkuttan,Naremaddepalli, Seetharamaiah Setty Sudarshan

申请号：

AU2016230759

公开号：

AU2016230759A1

申请日:

2016.03.09

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

The present invention relates to 3-substituted-1,2,4-oxadiazole and thiadiazole compounds of formula (I) or formula (II) and their use to inhibit the programmed cell death 1 (PD-1) signaling pathway and/or for treatment of disorders by inhibiting an immunosuppressive signal induced by PD-1, PD-L1 or PD-L2.

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