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Myocardial drug delivery apparatus and methods
专利权人:
Incube Labs; LLC
发明人:
IMRAN, Mir,SPEHR, Paul
申请号:
AU2017219161
公开号:
AU2017219161A1
申请日:
2017.08.29
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
#$%^&*AU2017219161A120170921.pdf#####MYOCARDIAL DRUG DELIVERY APPARATUS AND METHODS ABSTRACT An apparatus (10) for delivery of medication to a delivery site within the body of a patient, the apparatus (10) comprising: a drug storage device (30) configured to be implanted within the patient's body, the storage device (30) configured to store a plurality of solid form medication elements (100), each medication element (100) comprising at least one drug; a flexible delivery member (20) having a proximal and distal end (20ep, 20ed), the proximal end (20ep) coupled to the drug storage device (30), the delivery member (20) including a lumen (16) for advancement of the medication element (100) through the delivery member (20); an advancement member (70) configured to advance the medication element (100) through the delivery member lumen (16); and a capture chamber (80) coupled to the distal end (20ed) of the delivery member (20); the capture chamber (80) including a housing (81) having an interior volume (82) for receiving the medication element (100), the housing (81) including at least one porous section (87) allowing tissue fluids to seep in and out of the chamber (80); wherein the chamber (80) is configured to i) retain a medication element received from the delivery member (20); ii) dissolve the medication element in tissue fluids within the interior volume (82) to form a drug solution comprising the at least one drug; and iii) seep the drug solution from the interior volume (82) through the at least one porous section (87) to exterior tissue fluids to be diffusively delivered to the delivery site.
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