Abu-Reziq, Raed,Bar-Simantov, Haim,Sommer, William T.,Bilman, Nissim,Shapiro, Leora,Toledano, Ofer,Sriadibhatla, Srikan
申请号：
AU2014201268
公开号：
AU2014201268A1
申请日:
2014.03.07
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
#$%^&*AU2014201268A120140403.pdf#####Particles comprising a particulate matter coated by a metal oxide layer wherein: (i) said metal oxide layer has a width of 0.1 -10 micron and (ii) said particles are characterized in that when tested in a Dissolution Tester using Paddle Method in a medium, typically an organic-based solvent such as acetonitrile, iso propyl miristate, ethanol or methanol, in which said particulate matter is soluble, and a dissolution volume in which the concentration of the particulate matter is -lower than the solubility of the particulate matter, the time for releasing 50% w/w of the particulate matter from said particles is at least two-fold higher compared to the dissolution of the free form of the particulate matter having substantially the same particle size diameter as the particulate matter in said particles.
