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Stable perfluorocarbon emulsion for use as an artificial oxygen carrier
专利权人:
Natalya Y. Rapoport
发明人:
Natalya Y. Rapoport,Glenn D. Prestwich,Russell Morris Condie
申请号:
US13133126
公开号:
US08673984B2
申请日:
2009.12.08
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Perfluorocarbon emulsions having a high stability and good oxygen release are disclosed and described. These perfluorocarbon emulsions are typically for use as artificial oxygen carriers. The perfluorocarbon emulsions include a disperse phase of a perfluorocarbon and an emulsion stabilizer, and continuous phase. The emulsion stabilizer can primarily include a poly(ethylene oxide) block copolymer. These stabilized perfluorocarbon emulsions can be used in liquid and/or hydrogel phases of perfusion bioreactors or various other culture systems to enhance cell viability in thick tissue constructs, or as blood substitutes, although other applications may also be considered.
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