The National Institute for Biotechnology in the Negev, Ltd.;B.G. Negev Technologies and Applications Ltd., at Ben-Gurion University
发明人:
申请号:
EP16863784.1
公开号:
EP3373939A4
申请日:
2016.11.10
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
Provided are RNA inhibitory molecules, particularly siRNA molecules silencing the expression of Voltage-Dependent Ion Chanel-1 (VDAC1) for the induction of cancer stem cell differentiation and reduction of TAMs abundance and tumor angiogenesis, thereby preventing tumor invention and recurrence.