THE NATIONAL INSTITUTE FOR BIOTECHNOLOGY IN THE NEGEV LTD.;B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY
发明人:
Varda SHOSHAN-BARMATZ
申请号：
US15774795
公开号：
US20180327753A1
申请日:
2016.11.10
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Provided are RNA inhibitory molecules, particularly siRNA molecules silencing the expression of Voltage-Dependent Ion Chanel-1 (VDAC1) for the induction of cancer stem cell differentiation and reduction of TAMs abundance and tumor angiogenesis, thereby preventing tumor invention and recurrence.
