A needle device for delivering to the tissue a therapeutic agent, a lumen suitable for the connection of the pressure producing element, the therapeutic agent to pass through, and a needle barrel needle barrel of each , needle device is characterized in that it comprises an aperture which is suitable for increasing the cell membrane permeability of the therapeutic agent to be delivered to the tissue and controlling the pressure which is transmitted from the pressure producing element.治療用物質を組織に送達するための針装置であって、圧力生成要素との接続部と、治療用物質が通過するのに適した管腔と、針バレルとを含み;それぞれの針バレルが、圧力生成要素から伝達された圧力を制御かつ組織に送達して治療用物質の細胞膜透過性を増加させるのに適した開孔を含むことを特徴とする針装置。
