A PROCESS FOR THE PREPARATION OF DACLATASVIR DIHYDROCHLORIDE

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专利权人:

发明人:

DR NITIN SHARADCHANDRA PRADHAN,DR SACHIN ULHAS SONAVANE,MR DAYAGHAN GHANGADHAR PATIL,MR ROHAN ASHOK NIKAM,MR UTTAM SAKHARAM PUJARI

申请号：

IN201721003668

公开号：

IN201721003668A

申请日:

2017.02.01

申请国别(地区):

IN

年份:

2018

代理人:

摘要：

The present invention provides a process for the preparation of Daclatasvir dihydrochloride by using novel lH-benzotriazole activated MOC-L-Valine intermediate compound of structural formula IV. The present invention further provides the process for removal of Daclatasvir mono impurity compound of structural formula VII from Daclatasvir free base compound of structural formula II.

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