Adaptive Biotechnologies Corporation;Fred Hutchinson Cancer Research Center
发明人:
Robins, Harlan S.,Livingston, Robert J.,Bielas, Jason H.
申请号：
AU20120325791
公开号：
AU2012325791(B2)
申请日:
2012.10.19
申请国别(地区):
澳大利亚
年份:
2018
代理人:
摘要：
Compositions and methods are described for highly sensitive quantification of the relative representation of DNA from adaptive immune cells (e.g., T and/or B lymphocytes) in DNA extracted from complex mixtures of cells that include cells which are not adaptive immune cells. Included are methods for determining the relative presence in a tumor of tumor infiltrating lymphocytes (TIL), the relative presence of lymphocytes infiltrating a somatic tissue that is the target of an autoimmune disease, and the relative presence of lymphocytes infiltrating a transplanted organ.
