Mark Throsby,Robert Heinz Edward Friesen,Theodorus Hendrikus Jacobus Kwaks,Mandy Antonia Catharina Jongeneelen
申请号：
US13138941
公开号：
US08470327B2
申请日:
2010.05.06
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Binding molecules, such as human monoclonal antibodies, that bind to influenza virus comprising HA of the H3 subtype, such as H3N2, and have a broad neutralizing activity against such influenza virus. Provided are nucleic acid molecules encoding the antibodies, their sequences and compositions comprising the antibodies and methods of identifying or producing the antibodies. The antibodies can be used in the diagnosis, prophylaxis and/or treatment of an influenza virus H3N2 infection. The antibodies may provide cross-subtype protection, such that infections with H3, H7, and/or H10-based influenza subtypes can be prevented and/or treated.
