To provide an inhibitor for the metastasis of melanoma.SOLUTION: The present invention provides a melanoma metastasis inhibitor that comprises a material having the activity of inhibiting the functions of Eva1 protein in a metastasis tissue, particularly an antibody not having antibody-dependent cell-mediated cytotoxicity activity.SELECTED DRAWING: None【課題】メラノーマの転移抑制剤を提供。【解決手段】被転移組織におけるEva1タンパク質の機能を抑制する活性を有する物質、特に抗体依存性細胞傷害活性を有さない抗体であるメラノーマ転移阻害剤。【選択図】なし