Device for treatments of endoscopic resection/removal of tissues including: a handpiece an outer tubular element extending along a longitudinal axis including a proximal end, a distal end and a cutting opening at the distal end an inner tubular element rotatably accommodated in the outer tubular element the inner tubular element extending along a longitudinal axis and including a proximal end, a distal end and a cutting tip at its distal end a guide for rotating/oscillating the inner/outer tubular elements with respect to one another the guide including an electric motor and power-supply a first clutch keyed on the inner tubular element substantially at the proximal end of the inner tubular element a second clutch keyed on the distal end of the motor output shaft to axially slide on the motor output shaft and at least one elastic element to push the second clutch to couple with the first clutch.