This invention relates to a new crystalline form of the succinate salt of the epithelial sodium channel (ENaC) blocker 3-(3- {2-[(E)-3,5-Diamino-6-chloro-pyrazine-2-carbonylimino]- 1,3,8- triaza-spiro[4.5]decane-8-carbonyl} -benzenesulfonylamino)- propionic acid dipropylcarbamoylmethyl ester, pharmaceutical compositions comprising said crystalline form, uses of said crystal line form and pharmaceutical compositions, and methods for preparing said crystalline form.本發明涉及上皮鈉通道(ENaC)阻滯劑3-(3-{2-[(E)-3,5-二氨基-6-氯-吡嗪-2-羰基亞氨基]-1,3,8-三氮雜-螺[4.5]癸烷-8-羰基}-苯磺酰氨基)-丙酸二丙基氨基甲酰甲基酯琥珀酸鹽的新晶形、包含所述晶形的藥物組合物、所述晶形和藥物組合物的用途以及用於製備所述晶形的方法。
