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HIGHLY CONCENTRATED DRUG PARTICLES, FORMULATIONS, SUSPENSIONS AND USES THEREOF
专利权人:
Intarcia Therapeutics; Inc.
发明人:
Alessi, Thomas R.,Mercer, Ryan D.,Rohloff, Catherine M.,Yang, Bing
申请号:
AU2014268265
公开号:
AU2014268265A1
申请日:
2014.11.28
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
#$%^&*AU2014268265A120141218.pdf#####ABSTRACT The present invention consists of a pharmaceutical suspension formulation comprising, a particle formulation comprising, about 25 wt% to about 80 wt% drug, wherein the drug is a protein and about 75 wt% to about 20 wt% of one or more additional component, wherein the ratio of drug:additional component is between about 1:1 to about 5:1. and a non-aqueous, single-phase suspension vehicle comprising one or more polymer and one or more solvent wherein the suspension vehicle exhibits viscous fluid characteristics, and the particle formulation is homogeneously dispersed in the vehicle.
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