Imidazo pyrrolidone-2 compounds农业专利-农业专业知识服务系统

发明人:: P．菲雷,V．瓜格纳诺,V．瓜格納諾,P．霍尔策,P．霍爾策,J．卡伦,J．卡倫,廖律,R．马,R．馬,L．毛,K．马苏亚,K．馬蘇亞,A．施拉普巴赫,S．斯图兹,S．斯圖茲,A．沃佩尔,A．沃佩爾,P.菲雷,V.瓜格纳诺,V.瓜格納諾,P.霍尔策,P.霍爾策,J.卡伦,J.卡倫,R.马,R.馬,L.毛,K.马苏亚,K.馬蘇亞,A.施拉普巴赫,S.斯图兹,S.斯圖茲,A.沃佩尔,A.沃佩爾

摘要：: The present invention relates to formula (I) compounds: (I) as described herein, pharmaceutical preparation comprising these compounds, purposes of these compounds in the obstacle or disease that treatment MDM2 and/or MDM4 activity mediates, with the method for using these compounds in the obstacle or disease that treatment MDM2 and/or MDM4 activity mediates, and the combination comprising these compounds.本發明涉及式(I)化合物：如本文描述的(I)，包含這些化合物的藥物製劑，這些化合物在治療MDM2和/或MDM4活性介導的障礙或疾病中的用途，和在治療MDM2和/或MDM4活性介導的障礙或疾病中使用這些化合物的方法，以及包含這些化合物的組合。